Using Lucentis for Retinal Vein Occlusion Macular EdemaRetinal vein occlusion (RVO) is a blockage in a vein in the retina of the eye. There are two types of RVO: branch RVO and central RVO. Blockage of retinal veins can cause various complications, including macular edema (fluid accumulation in the macula of the eye). This fluid accumulation can cause distortion and blurriness in the center of one's vision.
Lucentis is approved for the treatment of macular edema following retinal vein occlusion (including branch RVO and central RVO). It has been shown to help reduce further vision loss and to help many people regain lost vision.
Using Lucentis for Diabetic Macular EdemaEye problems are common among people with diabetes. Diabetes can cause blood vessels in the eye to become leaky, leading to fluid accumulation in the macula. This is known as diabetic macular edema and can occur with type 1 diabetes or type 2 diabetes.
Lucentis is approved for the treatment of diabetic macular edema. It has been shown to help reduce further vision loss and to help many people regain lost vision.
Wet macular degeneration is caused by abnormal blood vessel growth in the back of the eye. The blood vessels grow behind the retina, underneath the macula (a part of the retina essential for detailed vision). These new blood vessels are not normal, and are weak and prone to leaking. Leaking causes damage to the macula, causing "wet" macular degeneration.
Macular edema following retinal vein occlusion is caused by a blockage of a retinal vein, leading to the leakage of fluid.
Lucentis is part of an antibody that is designed to bind to and inhibit vascular endothelial growth factor (VEGF-A). VEGF-A is a naturally occurring protein that encourages blood vessel leakage and the growth of new blood vessels (including abnormal blood vessels in wet macular degeneration). By binding to VEGF-A, Lucentis prevents this protein from encouraging new blood vessel growth and blood vessel leakage. This helps to slow down (or even reverse) vision loss and macular damage.