Macular Degeneration Home > Grape Seed Extract Dosage

There is no standard recommended dose for grape seed extract, as most dietary supplements have not been studied in clinical trials. Only vague "trial and error" dosing information is currently available. Studies have used grape seed extract dosages ranging from 40 mg daily up to 720 mg daily. It is best to follow the dosing guidelines provided with your particular product.

An Introduction to Dosing With Grape Seed Extract

It is difficult to recommend a safe and effective dosage for grape seed extract at this time. The best doses have not been scientifically established yet, as is common with natural products and dietary supplements.

What Is a Reasonable Grape Seed Extract Dose?

Because dietary supplements and foods do not need approval from the U.S. Food and Drug Administration (FDA), studies to find the safest and most effective dosages for dietary supplements or foods are rarely performed. Without such studies, only vague "trial and error" information is typically available. Even if good dosing information were available, there may be significant variability of the content, purity, and strength among different brands of the same dietary supplement, making consistently safe and effective dosing difficult. There may even be significant variability in the content, purity, and strength among different batches or lots of the exact same products.
Studies have used a wide range of grape seed extract dosages, ranging from 40 mg daily up to 720 mg daily. Since there is really no good information about grape seed extract dosing, it is reasonable to follow the dosing instructions provided on the label of your particular product.

General Information on Your Grape Seed Extract Dosage

Some considerations for people taking grape seed extract include the following:
  • If you decide to take a grape seed extract supplement, it is important to choose a trustworthy manufacturer, since supplements are not regulated as closely as drugs. Your pharmacist is a good source for information about which supplement manufacturers are most reliable. Products that are more expensive are not necessarily of a higher quality.
  • If you have any chronic health problems or take any prescription medications, it is a good idea to check with your healthcare provider before taking grape seed extract.
  • If you are unsure about anything related to your dosage or grape seed extract dosing in general, please talk with your healthcare provider or pharmacist.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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