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Macugen Uses

How Does Macugen Work?

Age-related wet macular degeneration is caused by abnormal blood vessel growth in the back of the eye. The blood vessels grow behind the retina, underneath the macula (a part of the retina that is essential for detailed vision). These new blood vessels are not normal and are weak and prone to leaking. Leaking causes damage to the macula, which causes"wet" macular degeneration.
 
Macugen is a molecule that is designed to bind to and inhibit vascular endothelial growth factor (VEGF). VEGF is a naturally occurring protein that encourages the growth of new blood vessels (including the abnormal blood vessels in wet macular degeneration). By binding to VEGF, Macugen prevents this protein from encouraging new blood vessel growth. This helps to slow down (or even reverse) vision loss and macular damage.
 

Macugen Uses in Children

Macugen is not approved for use in children. Talk to your healthcare provider about the benefits and risks of using the drug in children.
 

Off-Label Macugen Uses

On occasion, your healthcare provider may recommend Macugen for treating something other than the condition listed in this article. Currently, there are no universally accepted off-label uses of Macugen.
 

Macugen for Macular Degeneration

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