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Macugen Warnings and Precautions

Before starting treatment for macular degeneration with Macugen, warnings and precautions for the drug should be discussed with your healthcare provider. Make sure he or she knows about any allergies or infections you may have in or around the eyes. Macugen warnings and precautions also include being aware that the drug may cause retinal detachment or other eye problems and can temporarily increase pressure inside the eye.

Macugen: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Macugen® (pegaptanib sodium) if you have:
 
  • An infection in or around the eyes
  • Any allergies, including allergies to food, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
     
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 

Specific Macugen Warnings and Precautions

Warnings and precautions to be aware of prior to taking Macugen include the following:
 
  • As with any injection into the eye, Macugen can cause retinal detachment or other eye problems (although this is extremely rare). Retinal detachment is very serious and can lead to blindness. Your healthcare provider should monitor you closely to make sure you do not develop such problems. Let your healthcare provider know if you have any of the following side effects, which may be signs of serous problems:
 
    • Eye redness
    • Sensitivity to light
    • Vision changes.
 
  • Sometimes, Macugen injections cause a temporary increase in the pressure inside the eye. Your healthcare provider should monitor your eyes immediately after each injection to make sure that the pressure in your eye is not too high.
     
  • Macugen is unlikely to interact with other medications (see Macugen Drug Interactions).
     
  • Macugen is considered a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are not known. Talk to your healthcare provider about the risks and benefits of using the drug while pregnant (see Macugen and Pregnancy).
     
  • It is not known if Macugen passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Macugen and Breastfeeding).
     

Macugen for Macular Degeneration

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